Zane is the New York Times bestselling author of Afterburn, The Heat Seekers, Dear G-Spot, Gettin’ Buck Wild, The Hot Box, Total Eclipse of the Heart, Nervous, Skyscraper, Love is Never Painless, Shame on It All, and The Sisters of APF; the ebook short stories “I’ll be Home for Christmas” and “Everything Fades Away”; and editor for the Flava anthology series, including Z-Rated and Busy Bodies.

Her TV series, Zane’s Sex Chronicles, and The Jump Off are featured on Cinemax, and her bestselling novel Addicted is a major motion picture with Lionsgate Films.

She is the publisher of Strebor Books, an imprint of Atria Books/Simon & Schuster. Visit her online at EroticaNoir.com.

In 1997, Zane began writing erotic stories to pass the time after her children went to bed.  She was living in North Carolina and working as a sales representative. The stories developed a following on the Internet and she self-published The Sex Chronicles before landing a deal with Simon & Schuster.  Her work was the basis for the Cinemax program Zane's Sex Chronicles.  Her latest project, Zane's The Jump Off, premiered March 29, 2013, on Cinemax.

Zane is the publisher of Strebor Books/Atria Books/Simon and Schuster where she publishes 36–60 books a year by other authors.

In 2014, she was cited by Comptroller of Maryland Peter Franchot as one of Maryland's top tax cheats, owing the state $340,833.58.  On June 11, 2014, Zane filed for Chapter 7 bankruptcy in U.S. Bankruptcy Court in Maryland, claiming total liabilities of more than $3.4 million.  The first feature film based on one of her works, Addicted, was released by Lionsgate on October 10, 2014.

Her work is mentioned in sociologist Shayne Lee's book Erotic Revolutionaries: Black Women, Sexuality, and Popular Culture. In it, Lee discusses Zane's work as an example of "urban erotica [that helps] create safe spaces for black female characters to explore lust and embark upon sexual experimentation."